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maryjane or cocaine or one of these addictive medications or you can take valium or some other that hostile to psychotics and stuff as you take the first you get a genuine high however every consequent one is a little bitlower see end up needing to take increasingly elevated measurements to get the same impact and that is truly resistance or resilience and happens for all medications insulin is precisely the same as you take more insulin Diabazole  your body grows more imperviousness to it and now you see that it's really a genuine endless loop in light of the fact that what happens is that if your insulin level is high then it you get some insulin resistance as you get insulin resistance you get higher insulin levels as you get higher insulin levels.